The attraction in the UK capital made the decision to split up the couple of 11 years after hearing about the break-up which stunned the world on Tuesday (21.09.16).
'Twilight' hunk Robert Pattinson has been placed between them to split the statues up.
A photo of the separated models was uploaded to the official Madame Tussauds Twitter account, along with the caption: "Following the news that has shocked celebrity watchers worldwide, we can confirm we have separated Brad Pitt and Angelina Jolie's figures."
Angelina, 41, filed divorce papers in a Los Angeles court on Monday (19.09.16) with the documentation revealing the date of separation as September 15, 2016, and that she is seeking primary physical custody of their six children - Maddox, 15, Pax, 12, Zahara, 11, Shiloh, 10, and eight-year-old twins Knox and Vivienne.
Brad, 52, released a statement shortly after the news broke admitting he is "very saddened" by the end of his relationship.
It read: "I am very saddened by this, but what matters most now is the wellbeing of our kids. I kindly ask the press to give them the space they deserve during this challenging time."