The 'Bump 'N' Grind' star, who recently collaborated with the 19-year-old singer, thinks the 'Boyfriend' hitmaker can handle the media scrutiny after his recent bad behaviour.
In an interview with E! News, he said: "He's young with an old soul, so he can take it."
He added: "His struggle will determine his success. I ain't worried about him."
Justin bragged about his recent wild party on Friday night, claiming it was like a scene from 'The Great Gatsby'. Neighbours reportedly called the police three times due to the excessive noise.
R. Kelly said he hadn't known him long when the pair decided to work together on the track 'PYD' (Put You Down), which was released yesterday (18.11.13) as part of Justin's #MusicMondays Twitter campaign.
The 46-year-old star said: "We've known each other for a minute. "One time we sat in a hotel playing each other's songs for two hours. I love a few of the songs he did and he loves a few of the songs I did.
"We decided we would do things together, sending things back and forth and now it's phenomenal."
The R&B star also worked with Lady Gaga for her single 'Do What You Want' from her latest album 'ARTPOP'.
The two also performed a steamy rendition of the hit track during 'Saturday Night Live' over the weekend.