The 'Keeping Up With The Kardashians' stars were travelling in Bozeman, Montana today (21.02.15) when Khloé lost control of the car after skidding on ice, reports gossip website TMZ.
The car is believed to have crossed oncoming traffic before ending in a ditch after a semi-truck passed their vehicle and snow flicked up and covered the windscreen, leaving Khloé unable to see where she was going.
Police attended the accident and everyone involved is said to be OK.
It comes just two weeks after their father, Bruce Jenner, was involved in a fatal car crash - and his daughters "are trying to be there for him as much as they can."
A source close to 65-year-old Bruce said previously: "All the girls checked in with Bruce after the accident. All of them. They all wanted to make sure he was okay and to show their support. They really are trying to be there for him as much as they can right now. This is tough on him...
"Bruce is devastated. The accident happened right in front of his eyes and he stayed there the entire time watching everything. The woman who passed away was not in good shape and Bruce saw her body being taken out of the car.
"He knows he wasn't responsible but he still feels terrible. This past week was rough for him."
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