According to the Stomper, the image appears on the screen briefly in episode 19.
The Stomper wrote:
"Marvel's Agents of S.H.I.E.L.D., simply known as Agents of S.H.I.E.L.D is an American television series created for ABC, based on Marvel's comics.
"While watching episode 19 'The Only Light in the Darkness' of the series, approximately 35 minutes into the show, this striking image caught my eye.
"They show the character Skye looking at a portrait that resembles our Fullerton hotel and CBD buildings.
"So is that really Singapore or are we part of Agents of S.H.I.E.L.D. now?"